|
|
proto-zwittermicin_A-L-alanyl-[PKS] + L-leucine + L-methionine + O2 + NADPH <=> proto-zwittermicin_A + pyruvoyl-L-leucyl-L-methionine + NADP+ + H2O + polyketide-[acp]
|
2.3.1
|
–
|
| |
MetaCyc:
RXN-16941
|
|
|
|
(2R)-2-hydroxy-3-oxopropanoyl-[acp] + FAD + H2O <=> (2R)-2-hydroxymalonyl-[acp] + FADH2
|
1.2.98
|
–
|
| |
MetaCyc:
RXN-16916
|
|
|
|
L-serine + ATP <=> O-phospho-L-serine + ADP + H+
|
2.7.1.225
L-serine kinase (ATP)
|
–
|
| |
BRENDA:
BR52693
KEGG:
R12344
MetaCyc:
RXN-19819
|
|
|
|
L-2,3-diaminopropionic_acid + Carbamoyl_phosphate <=> L-Albizziin + phosphate + H+
|
2.1.3
|
–
|
| |
MetaCyc:
RXN-16917
|
|
|
|
N-[(2S)-2-amino-2-carboxyethyl]-L-glutamate + NAD+ + H2O <=> 2-oxoglutarate + L-2,3-diaminopropionic_acid + NADH + H+
|
1.5.1.51
N-[(2S)-2-amino-2-carboxyethyl]-L-glutamate dehydrogenase
|
–
|
| |
BRENDA:
BR51928
KEGG:
R11655
MetaCyc:
RXN-18393
|
|
|
|
L-seryl-[L-seryl-carrier_protein] + NAD+ <=> 2-aminomalonyl_semialdehyde-[L-seryl-carrier_protein] + NADH + H+
|
1.1.1
|
–
|
| |
MetaCyc:
RXN-16907
|
|
|
|
[acyl-carrier_protein] + 3-phospho-D-glyceroyl_phosphate + H2O <=> D-glyceryl-[acp] + phosphate
|
2.3.1
|
–
|
| |
MetaCyc:
RXN-16914
|
|
|
|
D-glyceryl-[acp] + NAD+ <=> (2R)-2-hydroxy-3-oxopropanoyl-[acp] + NADH + H+
|
1.1.1
|
–
|
| |
MetaCyc:
RXN-16915
|
|
|
|
proto-zwittermicin_A + H2O <=> zwittermicin_A + acyl-D-asparagine
|
3.4.11
|
–
|
| |
MetaCyc:
RXN-16934
|
|
|
|
fatty_acid + L-asparagine + L-serine + malonyl-CoA + aminomalonyl-[L-seryl-carrier_protein] + (2R)-2-hydroxymalonyl-[acp] + L-Albizziin + L-alanine + O2 + NADPH + H+ + polyketide-[acp] <=> proto-zwittermicin_A-L-alanyl-[PKS] + CO2 + NADP+ + H2O + holo-[L-seryl-carrier_protein] + [acyl-carrier_protein] + CoA
|
2.3.1
|
–
|
| |
MetaCyc:
RXN-16919
|
|
|
|
2-aminomalonyl_semialdehyde-[L-seryl-carrier_protein] + H2O + FAD <=> aminomalonyl-[L-seryl-carrier_protein] + FADH2
|
1.2.98
|
–
|
| |
MetaCyc:
RXN-16908
|
|
|
|
holo-[L-seryl-carrier_protein] + L-serine + ATP <=> L-seryl-[L-seryl-carrier_protein] + AMP + diphosphate
|
6.2.1.ae
|
–
|
| |
MetaCyc:
RXN-16906
|
|
|
|
O-phospho-L-serine + L-glutamate <=> N-[(2S)-2-amino-2-carboxyethyl]-L-glutamate + phosphate
|
2.5.1.140
N-(2-amino-2-carboxyethyl)-L-glutamate synthase
|
–
|
| |
BRENDA:
BR52061
KEGG:
R11705
MetaCyc:
RXN-18395
|
|
